The Neutrogena Healthy Skin Anti-Wrinkle Retinol Night Cream with Vitamin E and Pro-Vitamin B5 is a dermatologist-developed overnight moisturizer designed to help reduce the appearance of fine lines, wrinkles, and uneven skin texture while you sleep. It combines retinol, a proven anti-aging ingredient, with nourishing vitamins to support smoother, healthier-looking skin.

The cream works overnight to promote skin renewal, improve texture, and enhance radiance while providing hydration to help minimize the dryness that can sometimes occur with retinol use.

Key Ingredients

• Retinol – a vitamin A derivative that helps accelerate skin cell turnover, improve skin texture, and reduce the appearance of fine lines and wrinkles.
• Vitamin E – an antioxidant that helps protect the skin from environmental stressors and supports skin conditioning.
• Pro-Vitamin B5 (Panthenol) – helps soothe, hydrate, and strengthen the skin barrier.
• Glycerin – attracts moisture to keep skin hydrated and soft.

Benefits

✔ Helps reduce the appearance of fine lines and wrinkles

✔ Promotes smoother and more refined skin texture

✔ Supports skin renewal overnight

✔ Improves skin radiance and brightness

✔ Provides hydration while treating signs of aging

✔ Helps soften rough or uneven skin

✔ Contains antioxidants to support skin health

✔ Suitable for most skin types, including normal, combination, and mature skin

Texture & Finish

• Rich cream texture
• Absorbs well into the skin
• Provides overnight nourishment
• Leaves skin feeling soft and moisturized by morning
• Non-greasy finish for most skin types

Best For

• Fine lines and wrinkles
• Early signs of aging
• Dull skin
• Uneven skin texture
• Normal skin
• Combination skin
• Mature skin

How to Use

1. Cleanse and dry your skin thoroughly.
2. Apply a small amount evenly over the face and neck in the evening.
3. Avoid the immediate eye area.
4. Follow with a moisturizer if additional hydration is needed.
5. Start using 2–3 nights per week if you are new to retinol, then gradually increase frequency as tolerated.

Important Tips

• Use sunscreen every morning while using retinol products, as retinol can increase sun sensitivity.
• Mild dryness, peeling, or irritation may occur during the adjustment period.
• Avoid combining with multiple strong exfoliants (AHA/BHA) in the same routine when first starting.
• Patch testing is recommended for sensitive skin.

Suitable Skin Concerns

• Fine lines
• Wrinkles
• Dullness
• Rough texture
• Early aging signs
• Loss of radiance